基本信息：
中文名称 二氟-羟基-(亚异丙基二氧丙基)-丙酸乙酯
中文别名 (3R,S)-2,2-二氟-3-羟基-(2,2-二甲基二氧环戊-4-基)丙酸乙酯;吉西他滨中间体T3;(3R,S)-2,2-二氟-3-羟基-3-(2,2-二甲基二氧环戊-4-基)丙酸乙酯;乙基-3-(2,2-二甲基-1,3-二氧戊烷-4-基)-2,2-二氟-3-羟基丙酸;(R)-3-((R)-2,2-二甲基-1,3-二氧五环-4-基)-2,2-二氟-3-羟基-丙酸乙酯;
英文名称 Ethyl (3R,S)-2,2-difluoro-3-hydroxy-3-(2,2-dimethyldioxolan-4-yl)propionate
英文别名 ethyl 2,2-difluoro-3(R)-hydroxy-3-((R)-2,2-dimethyldioxolan-4-yl)propionate;3-(2,2-Dimethyl[1,3]dioxolan-4-yl)-2,2-difluora-3-hydroxy-propionic acid ethyl ester;ethyl (3R)-3-(2,2-dimethyl-1,3-dioxolan-4-yl)-2,2-difluoro-3-hydroxypropanoate;Ethyl(3RS)-2,2-Difluoro-3-(2,2-Dimethylioxolan-4-yl)Propionate;(erytro) ethyl-3-(2,2-dimethyl-1,3-dioxolan-4-yl)-2,2-difluoro-3-hydroxy propionate;Ethyl(3R,S)-2,2-difluoro-3-hydroxy-3-(2,2-dimethyldioxolan-4-yl)propionate;D-ERYTHRO-PENTONIC ACID,2-DEOXY-2,2-DIFLUORO-4,5-O-(1-METHYLETHYLIDENE)-,ETHYL ESTER;Ethyl(3RS)-2,2-Difluoro-3-(2,2-dimethyldioxolan-4-yl)propionate;D-erythro-Pentonic acid,2-deoxy-2,2-difluoro-4,5-O-(1-methylethylidene)-,ethyl ester (9CI);ethyl (R)-2,2-difluoro-3-hydroxy-3-((R)-2,2-dimethyl-[1,3]dioxoran-4-yl)propionate;(R)-ethyl 3-((R)-2,2-dimethyl-1,3-dioxolan-4-yl)-2,2-difluoro-3-hydroxypropanoate;2-Deoxy-2,2-difluoro-4,5-O-isopropylidene-D-erythro-pentonic Acid Ethyl Ester;ethyl (D-erythro)-3-(hydroxy)-2,2-difluoro-3-(2,2-dimethyldioxalane-4-yl)propionate;ethyl 2,2-difluoro-3-hydroxy-3-(2,2-dimethyl-[1,3]dioxolan-4-yl)propionate;propionate (T3);ethyl (3R,4R)-3-(2,2-dimethyl-1,3-dioxolan-4-yl)-2,2-difluoro-3-hydroxypropanoate;2-DEOXY-2,2-DIFLUORO-4,5-O-(1-METHYLETHYLIDENE)-D-ERYTHROPENTONIC ACID ETHYL ESTER;
CAS号 95058-92-7
合成路线：
1.通过二氟溴乙酸乙酯和(R)-(+)-2,2-二甲基-1,3-二氧戊环-4-甲醛合成二氟-羟基-(亚异丙基二氧丙基)-丙酸乙酯，收率约75%；
2.通过二氟溴乙酸乙酯和(R)-(+)-2,2-二甲基-1,3-二氧戊环-4-甲醛合成二氟-羟基-(亚异丙基二氧丙基)-丙酸乙酯
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