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(2S)-2-[(叔丁氧羰基)氨基]-3-[4-(4,4,5,5-四甲基-1,3,2-二氧杂环戊硼烷-2-基)苯基]丙酸甲酯的合成路线有哪些?

提问时间:2021/4/21 17:43:26
(2S)-2-[(叔丁氧羰基)氨基]-3-[4-(4,4,5,5-四甲基-1,3,2-二氧杂环戊硼烷-2-基)苯基]丙酸甲酯有什么方法可以合成?

1条回复:

匿名
2021/4/21 17:43:26
基本信息:
中文名称 (2S)-2-[(叔丁氧羰基)氨基]-3-[4-(4,4,5,5-四甲基-1,3,2-二氧杂环戊硼烷-2-基)苯基]丙酸甲酯
英文名称 Methyl N-{[(2-methyl-2-propanyl)oxy]carbonyl}-4-(4,4,5,5-tetramet hyl-1,3,2-dioxaborolan-2-yl)-L-phenylalaninate
英文别名 N-Boc-(3S,4S)-4-amino-3-hydroxy-5-phenyl pentanoic acid;N-Boc-(3S,4S)-AHPPA;4-[[9H-fluoren-9-ylmethoxy(oxo)methyl]amino]-3-hydroxy-5-phenylpentanoic acid;N-BOC-(4-pinacolylborono)-L-phenylalanine methyl ester;(3S,4S)-4-(9-FLUORENYLMETHYLOXYCARBONYL)AMINO-3-HYDROXY-5-PHENYL-PENTANOIC ACID;(3S,4S)-N-tert-butoxycarbonyl-4-amino-3-hydroxy-5-phenylpentanoic acid;(S)-2-(tert-butoxycarbonylamino)-3-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)propanoic acid methyl ester;(3S,4S)-4-[(tert-butoxy)carbonylamino]-3-hydroxy-5-phenylpentanoic acid;(S)-methyl 2-(tert-butoxycarbonylamino)-3-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)propanoate;N-tert-butoxycarbonyl-(3S,4S)-4-amino-3-hydroxy-5-phenylpentanoic acid;methyl (S)-2-((tert-butoxycarbonyl)amino)-3-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)propanoate;methyl (2S)-2-[(tert-butoxycarbonyl)amino]-3-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]propionate;(S)-2-(tert-butoxycarbonylamino)-3-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)propanoic acid;N-Boc-phenyl statine;4-(9H-fluoren-9-ylmethoxycarbonylamino)-3-oxidanyl-5-phenyl-pentanoic acid;
CAS号 220587-29-1

合成路线:
1.通过N-叔丁氧羰基-L-苯丙氨酸甲酯和联硼酸频那醇酯合成(2S)-2-[(叔丁氧羰基)氨基]-3-[4-(4,4,5,5-四甲基-1,3,2-二氧杂环戊硼烷-2-基)苯基]丙酸甲酯


合成路线仅供参考
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