基本信息：
中文名称 4-[3-氯-4-(3-氟苄基氧)苯基氨基]-6-碘喹唑啉
中文别名 4-[3-氯-4-(3-氟苄氧基)苯胺基]-6-碘喹唑啉;4-[3-氯-4-(3-氟苄氧基)苯氨基]-6-碘喹唑啉;N-[3-氯-4-(3-氟苄氧基)苯基]-6-碘喹唑啉-4-胺;4-胺基-N-[3-氯-4-[(3-氟苄基)氧]苯基]-6-碘喹唑啉;
英文名称 N-[3-Chloro-4-(3-fluorobenzyloxy)phenyl]-6-iodoquinazolin-4-amine
英文别名 Lapatinib Intermediate 2;N-{3-chloro-4-[(3-fluorophenyl)Methoxy]phenyl}-6-iodoquinazolin-4-aMine;[3-Chloro-4-[(3-fluorobenzyl)oxy]phenyl](6-iodoquinazol;N-{3-chloro-4-[(3-fluorobenzyl)oxy]phenyl}-6-[5-({[2-(methanesulphonyl) ethyl]amino}methyl)-2-furyl]-4-quinazolin amine ditosylate;(6-iodo-(4-(3-fluorobenzyloxy)-3-chlorophenyl)-quinazolin-4-yl)amine;N-(3-Chloro-4-((3-fluorobenzyl)oxy)phenyl)-6-iodoquinazolin-4-amine;N-{3-Chloro-4-[(3-fluorophenyl)-methoxy]-phenyl}-6-iodo-4-quinazolinamine;4-[3-Chloro-4-(3-fluorobenzyloxy)anilino]-6-iodoquinazoline;N-{3-chloro-4-[(3-fluorobenzyl)oxy]phenyl}-6-iodo-4-quinazolinamine;4-[3-Chloro-4-(3-fluorobenzyloxy)phenylamino]-6-iodoquinazoline;N-[3-chloro-4-(3-fluorobenzyloxy)phenyl]-6-iodo-quinazolin-4yl-amine;N-(4-(3-fluorobenzyloxy)-3-chlorophenyl)-6-iodoquinazolin-4-aMine;4-[3-Chloro-4-(3-fluorobenzyloxy)phenylaMino]-6-iodoquinazoline;N-[3-chloro-4-(3-fluorobenzyloxy)-phenyl]-6-iodoquinazolin-4-amine;6-Iodo-4-[3-chloro-4-(3-fluorobenzyloxy)anilino]quinazoline;N-[3-Chloro-4-(3-fluorobenzyloxy)-phenyl]-6-iodoquinazolin-4-amine;N-[3-chloro-4-(3-fluorobenzyloxy)phenylJ-6-iodoquinazolin-4-amine;[3-chloro-4-(3-fluorobenzyloxy)phenyl]-(6-iodoquinazolin-4-yl)amine;
CAS号 231278-20-9
合成路线：
1.通过4-氯-6-碘喹唑啉和3-氯-4-(3-氟苄氧基)苯胺合成4-[3-氯-4-(3-氟苄基氧)苯基氨基]-6-碘喹唑啉，收率约87%；
2.通过3-氯-4-(3-氟苄氧基)苯胺合成4-[3-氯-4-(3-氟苄基氧)苯基氨基]-6-碘喹唑啉，收率约95%；
合成路线仅供参考