产品介绍 |
Zafirlukast是一种白三烯受体拮抗剂(LTRA),IC50为0.6μM,作用于CYP2C9,IC50为7.0 μM。 |
用途 |
A potent and selective CysLT1 receptor antagonist. |
生化机理 |
Zafirlukast is a potent subtype specific cysteinyl leukotriene type 1 receptor (CysLT1) antagonist; antiasthmatic. The cysteinyl-leukotrienes (CysLTs), LTC4 and LTD4, are potent mediators of asthma and hypersensitivity. They induce bronchoconstriction, augment microvascular permeability, and are vasoconstrictors of coronary arteries. |
包装 |
Z129979-50mg,Z129979-250mg in glass bottle |