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  • 雷诺嗪,95635-55-5,结构式
雷诺嗪,98.0%
雷诺嗪 ; Ranolazine
别名:雷诺嗪; N-(2,6-二甲基苯基)-4-[2-羟基-3-(2-甲氧苯氧基)丙基]-1-哌嗪乙酰胺;Ranexa; CVT 303; RS 43285-003 ;N-(2,6-Dimethylphenyl)-2-[4-[2-hydroxy-3-(2-methoxyphenoxy)propyl]piperazin-1-yl]acetamide
产品编号:BBP80111 ; CAS:95635-55-5; 分子式:C24H33N3O4 ; MDL: ; 品牌: 西力生物
货号 品牌 包装 库存 市场价 成交价 数量 购物车
BBP80111 西力生物 20mg ¥300 ¥285.0
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  • 商品详情
中文名: 雷诺嗪;雷诺嗪
中文别名: 雷诺嗪; N-(2,6-二甲基苯基)-4-[2-羟基-3-(2-甲氧苯氧基)丙基]-1-哌嗪乙酰胺;Ranexa; CVT 303; RS 43285-003
英文名称: Ranolazine
英文别名: N-(2,6-Dimethylphenyl)-2-[4-[2-hydroxy-3-(2-methoxyphenoxy)propyl]piperazin-1-yl]acetamide
CAS No.: 95635-55-5
分子式: C24H33N3O4
分子量: 427.54
性状:

属性

溶解性 <li>DMSO 86 mg/mL </li><li>Water <1 mg/mL </li><li class="b_bottom">Ethanol 20 mg/mL </li>

描述

产品介绍 Ranolazine 是一种抗心绞痛药物。
用途 An anti-ischemic agent which inhibits late sodium currents.
生化机理 Ranolazine is an anti-ischemic compound, which inhibits late sodium current that results in a reduction of Na+ dependent Ca2+ overload. Studies indicate that ATP production is shifted towards glucose oxidation by Ranolazine. This is due to the fact that more oxygen is required to phosphorylate the same amount of ATP during fatty acid oxidation than carbohydrate oxidation. These studies indicate that Ranolazine also inhibits oxygen consumption and ketogenesis by fatty acids in liver cells.
包装 R129868-100mg,R129868-500mg in glass bottle
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用途:

Ranolazine(Ranexa) is an antianginal medication. Ranolazine is believed to have its effects via altering the trans-cellular late sodium current. It is by altering the intracellular sodium level that ranolazine affects the sodium-dependent calcium channels during myocardial ischemia in rabbits. Thus, ranolazine indirectly prevents the calcium overload that causes cardiac ischemia in rats. [1]
[1] www.bentham.org/prc/samples/prc1-1/Higashi.pdf