基本信息:
中文名称 9-[4-羟基-3-(羟甲基)-丁基]-鸟嘌呤
中文别名 喷昔洛韦;哌昔洛韦;2-氨基-9-[4-羟基-3-(羟甲基)丁基]-1H-嘌呤-6-酮;9-[4-羟基-3-(羟甲基)丁基]鸟嘌呤;
英文名称 penciclovir
英文别名 peniciclovir;Penciclovir;2-Amino-1,9-dihydro-9-[4-hydroxy-3-(hydroxymethyl)butyl]-6H-purin-6-one;Denavir;Pencyclovir;2-amino-9-[4-hydroxy-3-(hydroxymethyl)butyl]-3H-purin-6-one;2-Amino-1,9-dihydro-9-[4-hydroxy-3-(hydroxymethyl)butyl]-6H-purin-6-one,BRL-39123;Penciclovirum;Adenovir;9-[4-Hydroxy-3-(hydroxymethyl)butyl]guanine;2-AMINO-9-[4-HYDROXY-3-(HYDROXYMETHYL)BUTYL]-3,9-DIHYDROPURIN-6-ONE,CERTIFIED REFERENCE MATERIAL;Vectavir;UNII-359HUE8FJC;2-Amino-9-[4-hydroxy-3-(hydroxymethyl)butyl]-1H-purin-6-one;
CAS号 39809-25-1
合成路线:
1.通过9-(4-乙酰氧基-3-乙酰氧甲基丁基)-2-氨基-6-氯嘌呤合成9-[4-羟基-3-(羟甲基)-丁基]-鸟嘌呤,收率约94%;

2.通过2-氨基-6-氯嘌呤合成9-[4-羟基-3-(羟甲基)-丁基]-鸟嘌呤,收率约25%;

合成路线仅供参考